Protein structure prediction center in CASP8
نویسندگان
چکیده
منابع مشابه
I-TASSER: fully automated protein structure prediction in CASP8.
The I-TASSER algorithm for 3D protein structure prediction was tested in CASP8, with the procedure fully automated in both the Server and Human sections. The quality of the server models is close to that of human ones but the human predictions incorporate more diverse templates from other servers which improve the human predictions in some of the distant homology targets. For the first time, th...
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The prediction of the 3-dimensional structure of a protein given its chemical composition (that is, its amino acid sequence), remains an elusive problem in spite of decades of research efforts. The rate of progress in the field is even stagnating, and much of the improvements seen in the last couple of years can be attributed to larger databases of experimentally determined protein structures, ...
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MOTIVATION Protein structure prediction is one of the most important problems in structural bioinformatics. Here we describe MULTICOM, a multi-level combination approach to improve the various steps in protein structure prediction. In contrast to those methods which look for the best templates, alignments and models, our approach tries to combine complementary and alternative templates, alignme...
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Hepatitis B virus (HBV) infection is a universal health problem and may result into acute, fulminant, chronic hepatitis liver cirrhosis, or hepatocellular carcinoma. Sequence for protein X of HBV was retrieved from Uniprot database. ProtParam from ExPAsy server was used to investigate the physicochemical properties of the protein. Homology modeling was carried out using Phyre2 server, and refin...
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ژورنال
عنوان ژورنال: Proteins: Structure, Function, and Bioinformatics
سال: 2009
ISSN: 0887-3585
DOI: 10.1002/prot.22517